LEARNING MATERIALS

• Stahl, S. (2021). Essential psychopharmacology: Neuroscientific Basis and Practical Applications (5th ed.). Cambridge University Press.
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• Stahl, S. (2020). Essential psychopharmacology: The prescriber’s guide (7th ed.). Cambridge University Press. (Reference as needed.)
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• Tom Lynch, PharmD.I (2007). The Effect of Cytochrome P450 Metabolism on Drug Response, Interactions, and Adverse Effects. American Family Physician, 76(3), 391–396.

For this assignment, choose one psychotropic drug that is metabolized by CYP450 enzymes and complete the following steps:

1. Write a summary introducing your chosen drug thoroughly in terms of its class, use, precautions, side effects, interactions, and overdose potential. Hypothesize the outcome of prescribing your chosen drug in the presence of its CYP450 inhibitor and inducer.
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3. Answer the following questions:
4.  

• 1. What are examples of drugs that will inhibit and induce the psychotropic drug you chose to study? What will happen in terms of side effects and symptoms in the patient if the psychotropic drug is prescribed along with either its (1) inhibitor or (2) inducer?
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• 2. For which CYP450 enzyme/s is it a substrate?
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• 3.What are the pharmacokinetic considerations when prescribing this medication (i.e., absorption, distribution, elimination)? Dietary considerations? Dosing times?

RUBRIC

Cites three or more references, using at least one new scholarly resource that was not provided in the course materials.

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