Which of the following pregnant women has most likely encountered the greatest increase in the risk that her child will have a fetal anomaly?

Which of the following pregnant women has most likely encountered the greatest increase in the risk that her child will have a fetal anomaly?

Answers:

A. A woman with diagnoses of syphilis and cirrhosis of the liver

B. A woman who has herpes simplex and who has recently recovered from endocarditis

C. A woman with chronic obstructive pulmonary syndrome and tuberculosis

D. A woman with diagnoses of insulin-dependent diabetes mellitus and peripheral neuropathy