A nurse is providing care for a 17-year-old boy who has experienced recurrent sinus and chest infections throughout his life and presently has enlarged tonsils and lymph nodes. Blood work indicated normal levels of B cells and free immunoglobulins but a lack of differentiation into normal plasma cells. The boy is currently receiving intravenous immunoglobulin (IVIG) therapy. What is the boy’s most likely diagnosis?

Answers:

A. X-linked hypogammaglobulinemia

B. Transient hypoglobulinemia

C. Common variable immunodeficiency

D. IgG subclass deficiency

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