PICOT is utilized by the health care community to identify and study a nursing practice problem. Consequently, PICOT examples that may provide insight into the use of the PICOT process may not be relevant to nursing practice as they are based on a medical practice problem. Define evidence-based practice. Describe the difference between a nursing practice problem and a medical practice problem. Provide one example of each. Discuss why is it important to ensure your PICOT is based on a nursing practice problem.