A 44-year-old patient presents with lump in the chest of approximately 2 cm in diameter. There is a slight dimple over the location of the lump and when the lump is manipulated it seems to be attached to the surrounding tissue. A lumpectomy is performed and the mass is sent to pathology. The pathology report comes back and the mass is confirmed to be an estrogen receptor negative, a progesterone receptor negative and a her2/neu receptor positive breast cancer.
• What are some of the risk factors for breast cancer?
• What tumor suppressor genes are associated with breast cancer?
• What tumor oncogenes are associated with breast cancer?
• Compare and contrast tumor suppressor genes from oncogenes?